Derrone Targeting the TGF Type 1 Receptor Kinase Improves Bleomycin-Mediated Pulmonary Fibrosis through Inhibition of Smad Signaling Pathway

Transforming growth factor-β (TGF-β) has a strong impact on the pathogenesis of pulmonary fibrosis. Therefore, in this study, we investigated whether derrone promotes anti-fibrotic effects on TGF-β1-stimulated MRC-5 lung fibroblast cells and bleomycin-induced lung fibrosis. Long-term treatment with...

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Detalles Bibliográficos
Autores principales: Molagoda, Ilandarage Menu Neelaka, Sanjaya, Sobarathne Senel, Lee, Kyoung Tae, Choi, Yung Hyun, Lee, Joyce H., Lee, Mi-Hwa, Kang, Chang-Hee, Lee, Chang-Min, Kim, Gi-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138718/
https://www.ncbi.nlm.nih.gov/pubmed/37108428
http://dx.doi.org/10.3390/ijms24087265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138718/
https://www.ncbi.nlm.nih.gov/pubmed/37108428
http://dx.doi.org/10.3390/ijms24087265

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