Azido-Ceramides, a Tool to Analyse SARS-CoV-2 Replication and Inhibition—SARS-CoV-2 Is Inhibited by Ceramides

Recently, we have shown that C6-ceramides efficiently suppress viral replication by trapping the virus in lysosomes. Here, we use antiviral assays to evaluate a synthetic ceramide derivative α-NH2-ω-N3-C6-ceramide (AKS461) and to confirm the biological activity of C6-ceramides inhibiting SARS-CoV-2....

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Detalles Bibliográficos
Autores principales: Brenner, Daniela, Geiger, Nina, Schlegel, Jan, Diesendorf, Viktoria, Kersting, Louise, Fink, Julian, Stelz, Linda, Schneider-Schaulies, Sibylle, Sauer, Markus, Bodem, Jochen, Seibel, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138768/
https://www.ncbi.nlm.nih.gov/pubmed/37108461
http://dx.doi.org/10.3390/ijms24087281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138768/
https://www.ncbi.nlm.nih.gov/pubmed/37108461
http://dx.doi.org/10.3390/ijms24087281

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