Mutability of druggable kinases and pro-inflammatory cytokines by their proximity to telomeres and A+T content

Mutations of protein kinases and cytokines are common and can cause cancer and other diseases. However, our understanding of the mutability in these genes remains rudimentary. Therefore, given previously known factors which are associated with high mutation rates, we analyzed how many genes encoding...

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Detalles Bibliográficos
Autores principales: McKnight, Ian, Raines, Regan, White, Hunter, Nosoudi, Nasim, Lee, Chan, Lee, Peter H. U., Shim, Joon W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138820/
https://www.ncbi.nlm.nih.gov/pubmed/37104389
http://dx.doi.org/10.1371/journal.pone.0283470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138820/
https://www.ncbi.nlm.nih.gov/pubmed/37104389
http://dx.doi.org/10.1371/journal.pone.0283470

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