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Constitutive secretion of pro-IL-18 allows keratinocytes to initiate inflammation during bacterial infection

Group A Streptococcus (GAS, Streptococcus pyogenes) is a professional human pathogen that commonly infects the skin. Keratinocytes are one of the first cells to contact GAS, and by inducing inflammation, they can initiate the earliest immune responses to pathogen invasion. Here, we characterized the...

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Detalles Bibliográficos
Autores principales: Johnson, Anders F., Sands, Jenna S., Trivedi, Keya M., Russell, Raedeen, LaRock, Doris L., LaRock, Christopher N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138833/
https://www.ncbi.nlm.nih.gov/pubmed/37068092
http://dx.doi.org/10.1371/journal.ppat.1011321