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Metabolite Identification of Isopropoxy Benzene Guanidine in Rat Liver Microsomes by Using UHPLC-Q-TOF-MS/MS

Isopropoxy benzene guanidine (IBG) is a guanidine derivative with antibacterial activity against multidrug-resistant bacteria. A few studies have revealed the metabolism of IBG in animals. The aim of the current study was to identify potential metabolic pathways and metabolites of IBG. The detection...

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Detalles Bibliográficos
Autores principales: Lu, Yixing, Zhang, Wanying, Zhang, Yongxiang, Wu, Sujuan, Ma, Minglang, Peng, Xianfeng, Zeng, Zhenling, Zeng, Dongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138866/
https://www.ncbi.nlm.nih.gov/pubmed/37108473
http://dx.doi.org/10.3390/ijms24087313