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SHMT2 Promotes Gastric Cancer Development through Regulation of HIF1α/VEGF/STAT3 Signaling

The metabolic enzymes involved in one-carbon metabolism are closely associated with tumor progression and could be potential targets for cancer therapy. Recent studies showed that serine hydroxymethyltransferase 2 (SHMT2), a crucial enzyme in the one-carbon metabolic pathway, plays a key role in tum...

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Detalles Bibliográficos
Autores principales: Wang, Weida, Wang, Mingjin, Du, Tingting, Hou, Zhenyan, You, Shen, Zhang, Sen, Ji, Ming, Xue, Nina, Chen, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138966/
https://www.ncbi.nlm.nih.gov/pubmed/37108312
http://dx.doi.org/10.3390/ijms24087150