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Nordalbergin Exerts Anti-Neuroinflammatory Effects by Attenuating MAPK Signaling Pathway, NLRP3 Inflammasome Activation and ROS Production in LPS-Stimulated BV2 Microglia

Microglia-associated neuroinflammation is recognized as a critical factor in the pathogenesis of neurodegenerative diseases; however, there is no effective treatment for the blockage of neurodegenerative disease progression. In this study, the effect of nordalbergin, a coumarin isolated from the woo...

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Detalles Bibliográficos
Autores principales: Lo, Jung, Wu, Hsin-En, Liu, Ching-Chih, Chang, Kun-Che, Lee, Po-Yen, Liu, Po-Len, Huang, Shu-Pin, Wu, Pei-Chang, Lin, Tzu-Chieh, Lai, Yu-Hung, Chang, Yo-Chen, Chen, Yuan-Ru, Lee, Sheng-I, Huang, Yu-Kai, Wang, Shu-Chi, Li, Chia-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138998/
https://www.ncbi.nlm.nih.gov/pubmed/37108458
http://dx.doi.org/10.3390/ijms24087300