Glucocorticoid Receptor and β-Catenin Interact in Prostate Cancer Cells and Their Co-Inhibition Attenuates Tumorsphere Formation, Stemness, and Docetaxel Resistance

Therapy resistance hinders the efficacy of anti-androgen therapies and taxane-based chemotherapy for advanced prostate cancer (PCa). Glucocorticoid receptor (GR) signaling mediates resistance to androgen receptor signaling inhibitors (ARSI) and has also been recently implicated in PCa resistance to...

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Detalles Bibliográficos
Autores principales: Martinez, Shannalee R., Elix, Catherine C., Ochoa, Pedro T., Sanchez-Hernandez, Evelyn S., Alkashgari, Hossam R., Ortiz-Hernandez, Greisha L., Zhang, Lubo, Casiano, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139020/
https://www.ncbi.nlm.nih.gov/pubmed/37108293
http://dx.doi.org/10.3390/ijms24087130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139020/
https://www.ncbi.nlm.nih.gov/pubmed/37108293
http://dx.doi.org/10.3390/ijms24087130

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