Identification of Potential p38γ Inhibitors via In Silico Screening, In Vitro Bioassay and Molecular Dynamics Simulation Studies

Protein kinase p38γ is an attractive target against cancer because it plays a pivotal role in cancer cell proliferation by phosphorylating the retinoblastoma tumour suppressor protein. Therefore, inhibition of p38γ with active small molecules represents an attractive alternative for developing anti-...

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Detalles Bibliográficos
Autores principales: Cheng, Zixuan, Bhave, Mrinal, Hwang, Siaw San, Rahman, Taufiq, Chee, Xavier Wezen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139033/
https://www.ncbi.nlm.nih.gov/pubmed/37108523
http://dx.doi.org/10.3390/ijms24087360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139033/
https://www.ncbi.nlm.nih.gov/pubmed/37108523
http://dx.doi.org/10.3390/ijms24087360

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