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Neural Isoforms of Agrin Are Generated by Reduced PTBP1−RNA Interaction Network Spanning the Neuron−Specific Splicing Regions in AGRN

Agrin is a heparan sulfate proteoglycan essential for the clustering of acetylcholine receptors at the neuromuscular junction. Neuron−specific isoforms of agrin are generated by alternative inclusion of three exons, called Y, Z8, and Z11 exons, although their processing mechanisms remain elusive. We...

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Detalles Bibliográficos
Autores principales: Bushra, Samira, Lin, Ying-Ni, Joudaki, Atefeh, Ito, Mikako, Ohkawara, Bisei, Ohno, Kinji, Masuda, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139058/
https://www.ncbi.nlm.nih.gov/pubmed/37108583
http://dx.doi.org/10.3390/ijms24087420