Novel Isoform DTX3c Associates with UBE2N-UBA1 and Cdc48/p97 as Part of the EphB4 Degradation Complex Regulated by the Autocrine IGF-II/IR(A) Signal in Malignant Mesothelioma

EphB4 angiogenic kinase over-expression in Mesothelioma cells relies upon a degradation rescue signal provided by autocrine IGF-II activation of Insulin Receptor A. However, the identity of the molecular machinery involved in EphB4 rapid degradation upon IGF-II signal deprivation are unknown. Using...

Descripción completa

Detalles Bibliográficos
Autores principales: Scalia, Pierluigi, Merali, Carmen, Barrero, Carlos, Suma, Antonio, Carnevale, Vincenzo, Merali, Salim, Williams, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139083/
https://www.ncbi.nlm.nih.gov/pubmed/37108544
http://dx.doi.org/10.3390/ijms24087380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139083/
https://www.ncbi.nlm.nih.gov/pubmed/37108544
http://dx.doi.org/10.3390/ijms24087380

Ejemplares similares