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Novel Isoform DTX3c Associates with UBE2N-UBA1 and Cdc48/p97 as Part of the EphB4 Degradation Complex Regulated by the Autocrine IGF-II/IR(A) Signal in Malignant Mesothelioma
EphB4 angiogenic kinase over-expression in Mesothelioma cells relies upon a degradation rescue signal provided by autocrine IGF-II activation of Insulin Receptor A. However, the identity of the molecular machinery involved in EphB4 rapid degradation upon IGF-II signal deprivation are unknown. Using...
Autores principales: | Scalia, Pierluigi, Merali, Carmen, Barrero, Carlos, Suma, Antonio, Carnevale, Vincenzo, Merali, Salim, Williams, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139083/ https://www.ncbi.nlm.nih.gov/pubmed/37108544 http://dx.doi.org/10.3390/ijms24087380 |
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