In Vitro and In Vivo Effects of the Combination of Polypurine Reverse Hoogsteen Hairpins against HER-2 and Trastuzumab in Breast Cancer Cells

Therapeutic oligonucleotides are powerful tools for the inhibition of potential targets involved in cancer. We describe the effect of two Polypurine Reverse Hoogsteen (PPRH) hairpins directed against the ERBB2 gene, which is overexpressed in positive HER-2 breast tumors. The inhibition of their targ...

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Detalles Bibliográficos
Autores principales: López-Aguilar, Ester, Fernández-Nogueira, Patricia, Fuster, Gemma, Carbó, Neus, Ciudad, Carlos J., Noé, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139100/
https://www.ncbi.nlm.nih.gov/pubmed/37108234
http://dx.doi.org/10.3390/ijms24087073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139100/
https://www.ncbi.nlm.nih.gov/pubmed/37108234
http://dx.doi.org/10.3390/ijms24087073

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