Lauric Acid Overcomes Hypoxia-Induced Gemcitabine Chemoresistance in Pancreatic Ductal Adenocarcinoma

Although gemcitabine (GEM) is widely used in chemotherapy for pancreatic ductal adenocarcinoma (PDA), drug resistance restricts its clinical effectiveness. To examine the mechanism of GEM resistance, we established two GEM-resistant cell lines from human PDA cells by continuous treatment with GEM an...

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Detalles Bibliográficos
Autores principales: Takagi, Tadataka, Fujiwara-Tani, Rina, Mori, Shiori, Kishi, Shingo, Nishiguchi, Yukiko, Sasaki, Takamitsu, Ogata, Ruiko, Ikemoto, Ayaka, Sasaki, Rika, Ohmori, Hitoshi, Luo, Yi, Bhawal, Ujjal Kumar, Sho, Masayuki, Kuniyasu, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139117/
https://www.ncbi.nlm.nih.gov/pubmed/37108667
http://dx.doi.org/10.3390/ijms24087506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139117/
https://www.ncbi.nlm.nih.gov/pubmed/37108667
http://dx.doi.org/10.3390/ijms24087506

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