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Transcriptional Activation of a Pro-Inflammatory Response (NF-κB, AP-1, IL-1β) by the Vibrio cholerae Cytotoxin (VCC) Monomer through the MAPK Signaling Pathway in the THP-1 Human Macrophage Cell Line

This study describes, to some extent, the VCC contribution as an early stimulation of the macrophage lineage. Regarding the onset of the innate immune response caused by infection, the β form of IL-1 is the most important interleukin involved in the onset of the inflammatory innate response. Activat...

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Detalles Bibliográficos
Autores principales: Escartín-Gutiérrez, Julio Rodrigo, Ponce-Figueroa, Mariana, Torres-Vega, Miguel Ángel, Aguilar-Faisal, Leopoldo, Figueroa-Arredondo, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139130/
https://www.ncbi.nlm.nih.gov/pubmed/37108435
http://dx.doi.org/10.3390/ijms24087272