Mycolactone: A Broad Spectrum Multitarget Antiviral Active in the Picomolar Range for COVID-19 Prevention and Cure

We have previously shown computationally that Mycolactone (MLN), a toxin produced by Mycobacterium ulcerans, strongly binds to Munc18b and other proteins, presumably blocking degranulation and exocytosis of blood platelets and mast cells. We investigated the effect of MLN on endocytosis using simila...

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Detalles Bibliográficos
Autores principales: Asiedu, Seth Osei, Gupta, Yash, Nicolaescu, Vlad, Gula, Haley, Caulfield, Thomas R., Durvasula, Ravi, Kempaiah, Prakasha, Kwofie, Samuel K., Wilson, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139166/
https://www.ncbi.nlm.nih.gov/pubmed/37108313
http://dx.doi.org/10.3390/ijms24087151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139166/
https://www.ncbi.nlm.nih.gov/pubmed/37108313
http://dx.doi.org/10.3390/ijms24087151

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