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Mycolactone: A Broad Spectrum Multitarget Antiviral Active in the Picomolar Range for COVID-19 Prevention and Cure
We have previously shown computationally that Mycolactone (MLN), a toxin produced by Mycobacterium ulcerans, strongly binds to Munc18b and other proteins, presumably blocking degranulation and exocytosis of blood platelets and mast cells. We investigated the effect of MLN on endocytosis using simila...
Autores principales: | Asiedu, Seth Osei, Gupta, Yash, Nicolaescu, Vlad, Gula, Haley, Caulfield, Thomas R., Durvasula, Ravi, Kempaiah, Prakasha, Kwofie, Samuel K., Wilson, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139166/ https://www.ncbi.nlm.nih.gov/pubmed/37108313 http://dx.doi.org/10.3390/ijms24087151 |
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