Unravelling the Impact of Cyclic Mechanical Stretch in Keratoconus—A Transcriptomic Profiling Study

Biomechanical and molecular stresses may contribute to the pathogenesis of keratoconus (KC). We aimed to profile the transcriptomic changes in healthy primary human corneal (HCF) and KC-derived cells (HKC) combined with TGFβ1 treatment and cyclic mechanical stretch (CMS), mimicking the pathophysiolo...

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Detalles Bibliográficos
Autores principales: Akoto, Theresa, Cai, Jingwen, Nicholas, Sarah, McCord, Hayden, Estes, Amy J., Xu, Hongyan, Karamichos, Dimitrios, Liu, Yutao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139219/
https://www.ncbi.nlm.nih.gov/pubmed/37108600
http://dx.doi.org/10.3390/ijms24087437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139219/
https://www.ncbi.nlm.nih.gov/pubmed/37108600
http://dx.doi.org/10.3390/ijms24087437

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