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Unravelling the Impact of Cyclic Mechanical Stretch in Keratoconus—A Transcriptomic Profiling Study
Biomechanical and molecular stresses may contribute to the pathogenesis of keratoconus (KC). We aimed to profile the transcriptomic changes in healthy primary human corneal (HCF) and KC-derived cells (HKC) combined with TGFβ1 treatment and cyclic mechanical stretch (CMS), mimicking the pathophysiolo...
Autores principales: | Akoto, Theresa, Cai, Jingwen, Nicholas, Sarah, McCord, Hayden, Estes, Amy J., Xu, Hongyan, Karamichos, Dimitrios, Liu, Yutao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139219/ https://www.ncbi.nlm.nih.gov/pubmed/37108600 http://dx.doi.org/10.3390/ijms24087437 |
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