Diclofenac does not interact with codeine metabolism in vivo: A study in healthy volunteers

BACKGROUND: Previously, we have demonstrated a marked inhibition of codeine glucuronidation by diclofenac in human liver tissue homogenate. We therefore aimed to investigate whether diclofenac inhibits glucuronidation of codeine also in vivo in healthy volunteers. METHODS: In a randomised, placebo-c...

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Detalles Bibliográficos
Autores principales: Ammon, Susanne, Marx, Claudia, Behrens, Christoph, Hofmann, Ute, Mürdter, Thomas, Griese, Ernst-Ulrich, Mikus, Gerd
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101395/
https://www.ncbi.nlm.nih.gov/pubmed/11943073
http://dx.doi.org/10.1186/1472-6904-2-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101395/
https://www.ncbi.nlm.nih.gov/pubmed/11943073
http://dx.doi.org/10.1186/1472-6904-2-2

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