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Diclofenac does not interact with codeine metabolism in vivo: A study in healthy volunteers
BACKGROUND: Previously, we have demonstrated a marked inhibition of codeine glucuronidation by diclofenac in human liver tissue homogenate. We therefore aimed to investigate whether diclofenac inhibits glucuronidation of codeine also in vivo in healthy volunteers. METHODS: In a randomised, placebo-c...
Autores principales: | Ammon, Susanne, Marx, Claudia, Behrens, Christoph, Hofmann, Ute, Mürdter, Thomas, Griese, Ernst-Ulrich, Mikus, Gerd |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101395/ https://www.ncbi.nlm.nih.gov/pubmed/11943073 http://dx.doi.org/10.1186/1472-6904-2-2 |
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