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Patterning precision under non-linear morphogen decay and molecular noise

Morphogen gradients can instruct cells about their position in a patterned tissue. Non-linear morphogen decay has been suggested to increase gradient precision by reducing the sensitivity to variability in the morphogen source. Here, we use cell-based simulations to quantitatively compare the positi...

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Detalles Bibliográficos
Autores principales: Adelmann, Jan Andreas, Vetter, Roman, Iber, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139688/
https://www.ncbi.nlm.nih.gov/pubmed/37102505
http://dx.doi.org/10.7554/eLife.84757