Calaxin stabilizes the docking of outer arm dyneins onto ciliary doublet microtubule in vertebrates

Outer arm dynein (OAD) is the main force generator of ciliary beating. Although OAD loss is the most frequent cause of human primary ciliary dyskinesia, the docking mechanism of OAD onto the ciliary doublet microtubule (DMT) remains elusive in vertebrates. Here, we analyzed the functions of Calaxin/...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Hiroshi, Morikawa, Motohiro, Kikkawa, Masahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139691/
https://www.ncbi.nlm.nih.gov/pubmed/37057896
http://dx.doi.org/10.7554/eLife.84860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139691/
https://www.ncbi.nlm.nih.gov/pubmed/37057896
http://dx.doi.org/10.7554/eLife.84860

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