EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environment

Aberrant expression of ecotropic viral integration site-1 (EVI1(+)) is associated with very poor outcomes in acute myeloid leukemia (AML), mechanisms of which are only partially understood. Using the green fluorescent protein reporter system to monitor EVI1 promoter activity, we demonstrated that Ev...

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Detalles Bibliográficos
Autores principales: Masamoto, Yosuke, Chiba, Akira, Mizuno, Hideaki, Hino, Toshiya, Hayashida, Hiroki, Sato, Tomohiko, Bando, Masashige, Shirahige, Katsuhiko, Kurokawa, Mineo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139867/
https://www.ncbi.nlm.nih.gov/pubmed/36269819
http://dx.doi.org/10.1182/bloodadvances.2022008018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139867/
https://www.ncbi.nlm.nih.gov/pubmed/36269819
http://dx.doi.org/10.1182/bloodadvances.2022008018

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