Targeting the contact system in a rabbit model of extracorporeal membrane oxygenation

Previous studies suggested that contact pathway factors drive thrombosis in mechanical circulation. We used a rabbit model of veno-arterial extracorporeal circulation (VA-ECMO) to evaluate the role of factors XI and XII in ECMO-associated thrombosis and organ damage. Factors XI and XII (FXI, FXII) w...

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Detalles Bibliográficos
Autores principales: Tweddell, James S., Kharnaf, Mousa, Zafar, Farhan, Riggs, Kyle W., Reagor, James A., Monia, Brett P., Revenko, Alexey, Leino, Daniel G., Owens, A. Phillip, Martin, Janine K., Gourley, Benjamin, Rosenfeldt, Leah, Palumbo, Joseph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139951/
https://www.ncbi.nlm.nih.gov/pubmed/36240297
http://dx.doi.org/10.1182/bloodadvances.2022007586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139951/
https://www.ncbi.nlm.nih.gov/pubmed/36240297
http://dx.doi.org/10.1182/bloodadvances.2022007586

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