Cargando…

Targeting the contact system in a rabbit model of extracorporeal membrane oxygenation

Previous studies suggested that contact pathway factors drive thrombosis in mechanical circulation. We used a rabbit model of veno-arterial extracorporeal circulation (VA-ECMO) to evaluate the role of factors XI and XII in ECMO-associated thrombosis and organ damage. Factors XI and XII (FXI, FXII) w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tweddell, James S., Kharnaf, Mousa, Zafar, Farhan, Riggs, Kyle W., Reagor, James A., Monia, Brett P., Revenko, Alexey, Leino, Daniel G., Owens, A. Phillip, Martin, Janine K., Gourley, Benjamin, Rosenfeldt, Leah, Palumbo, Joseph S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Hematology 2022
Materias:	Thrombosis and Hemostasis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139951/ https://www.ncbi.nlm.nih.gov/pubmed/36240297 http://dx.doi.org/10.1182/bloodadvances.2022007586

Ejemplares similares

Histidine-rich glycoprotein attenuates catheter thrombosis
por: Malik, Rida A., et al.
Publicado: (2023)

Thrombin-mediated activation of PAR1 enhances doxorubicin-induced cardiac injury in mice
por: Grover, Steven P., et al.
Publicado: (2022)

Mapping the prothrombin-binding site of pseutarin C by site-directed PEGylation
por: Üstok, Fatma Işık, et al.
Publicado: (2022)

Return emergency department visits for recurrent pulmonary embolism symptoms in children and adolescents
por: Egan-Sherry, Dana, et al.
Publicado: (2023)

Morbidities and mortality in patients with hereditary thrombotic thrombocytopenic purpura
por: Borogovac, Azra, et al.
Publicado: (2022)

Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain
por: Andersson, Helena M., et al.
Publicado: (2010)

Novel cysteine substitution p.(Cys1084Tyr) causes variable expressivity of qualitative and quantitative VWF defects
por: Rawley, Orla, et al.
Publicado: (2022)

The clinical and laboratory diagnosis of vaccine-induced immune thrombotic thrombocytopenia
por: Bissola, Anna-Lise, et al.
Publicado: (2022)

Laminin G1 residues of protein S mediate its TFPI cofactor function and are competitively regulated by C4BP
por: Teraz-Orosz, Adrienn, et al.
Publicado: (2022)

A transcriptome analysis of basal and stimulated VWF release from endothelial cells derived from patients with type 1 VWD
por: Kloosterman, Robert, et al.
Publicado: (2022)

Cleavage of talin by calpain promotes platelet-mediated fibrin clot contraction
por: Fong, Karen P., et al.
Publicado: (2021)

GRK2 regulates ADP signaling in platelets via P2Y(1) and P2Y(12)
por: Zhao, Xuefei, et al.
Publicado: (2022)

Management strategies following slightly out-of-range INRs: watchful waiting vs dose changes
por: Remer, Hallie B., et al.
Publicado: (2022)

Small interfering RNA–mediated allele-selective silencing of von Willebrand factor in vitro and in vivo
por: Jongejan, Yvonne K., et al.
Publicado: (2023)

S100A8/A9 drives the formation of procoagulant platelets through GPIbα
por: Colicchia, Martina, et al.
Publicado: (2022)

Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude
por: Li, Meiquan, et al.
Publicado: (2022)

VWF–ADAMTS13 axis dysfunction in children with sickle cell disease treated with hydroxycarbamide vs blood transfusion
por: Fogarty, Helen, et al.
Publicado: (2023)

Postdischarge thromboembolic outcomes and mortality of hospitalized patients with COVID-19: the CORE-19 registry
por: Giannis, Dimitrios, et al.
Publicado: (2021)

The interplay between tissue plasminogen activator domains and fibrin structures in the regulation of fibrinolysis: kinetic and microscopic studies
por: Longstaff, Colin, et al.
Publicado: (2011)

Harmful or Physiologic: Diagnosing Fibrinolysis Shutdown in a Trauma Cohort With Rotational Thromboelastometry
por: Gomez-Builes, J. Carolina, et al.
Publicado: (2018)

Platelets inhibit apoptotic lung epithelial cell death and protect mice against infection-induced lung injury
por: Bain, William, et al.
Publicado: (2019)

Targeting complement activation in COVID-19
por: Kulkarni, Hrishikesh S., et al.
Publicado: (2020)

Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition
por: Yu, Jia, et al.
Publicado: (2020)

COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection
por: Al-Samkari, Hanny, et al.
Publicado: (2020)

COVID-19 coagulopathy, thrombosis, and bleeding
por: Chan, Noel C., et al.
Publicado: (2020)

Frequency of venous thromboembolism in 6513 patients with COVID-19: a retrospective study
por: Hill, Jason B., et al.
Publicado: (2020)

A toolkit for the collection of thrombosis-related data elements in COVID-19 clinical studies
por: Siegal, Deborah M., et al.
Publicado: (2020)

Incidence of symptomatic, image-confirmed venous thromboembolism following hospitalization for COVID-19 with 90-day follow-up
por: Salisbury, Richard, et al.
Publicado: (2020)

A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice
por: Østergaard, Henrik, et al.
Publicado: (2021)

COVID-19 and VITT: same or different?
por: Arepally, Gowthami M.
Publicado: (2021)

von Willebrand factor antigen levels are associated with burden of rare nonsynonymous variants in the VWF gene
por: Sadler, Brooke, et al.
Publicado: (2021)

An alternate covalent form of platelet αIIbβ3 integrin that resides in focal adhesions and has altered function
por: Pijning, Aster E., et al.
Publicado: (2021)

Novel mechanism regulating tissue factor activity
por: Nieuwland, Rienk
Publicado: (2021)

The incidence of cancer-associated thrombosis is increasing over time
por: Mahajan, Anjlee, et al.
Publicado: (2022)

The binding of autotaxin to integrins mediates hyperhomocysteinemia-potentiated platelet activation and thrombosis in mice and humans
por: Han, Lulu, et al.
Publicado: (2021)

Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans
por: Alharbi, Abdulmajeed, et al.
Publicado: (2021)

Polyphosphate expression by cancer cell extracellular vesicles mediates binding of factor XII and contact activation
por: Shim, Young Jun, et al.
Publicado: (2021)

Most anti-PF4 antibodies in vaccine-induced immune thrombotic thrombocytopenia are transient
por: Schönborn, Linda, et al.
Publicado: (2022)

PKM2 promotes neutrophil activation and cerebral thromboinflammation: therapeutic implications for ischemic stroke
por: Dhanesha, Nirav, et al.
Publicado: (2022)

Contact and intrinsic coagulation pathways are activated and associated with adverse clinical outcomes in COVID-19
por: Henderson, Michael W., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tmj920epsggr1oifr33chb0cal