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Optogenetic activation of UCP1-dependent thermogenesis in brown adipocytes

Brown adipocytes are unique in that they expend energy and produce heat to maintain euthermia through expression of uncoupling protein-1 (UCP1). Given their propensity to stimulate weight loss and promote resistance to obesity, they are a compelling interventional target for obesity-related disorder...

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Detalles Bibliográficos
Autores principales: Doucette, Chad C., Nguyen, Daniel C., Barteselli, Davide, Blanchard, Sophia, Pelletier, Mason, Kesharwani, Devesh, Jachimowicz, Ed, Su, Su, Karolak, Michele, Brown, Aaron C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139976/
https://www.ncbi.nlm.nih.gov/pubmed/37123235
http://dx.doi.org/10.1016/j.isci.2023.106560