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Non-viral chimeric antigen receptor (CAR) T cells going viral

Chimeric antigen receptor (CAR) T cell therapy has made significant strides in the treatment of B-cell malignancies, but its application in treating solid tumors still poses significant challenges. Particularly, the widespread use of viral vectors to deliver CAR transgenes into T cells comes with li...

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Detalles Bibliográficos
Autores principales: Balke-Want, H., Keerthi, V., Cadinanos-Garai, A., Fowler, C., Gkitsas, N., Brown, A.K., Tunuguntla, R., Abou-el-Enein, M., Feldman, S.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139995/
https://www.ncbi.nlm.nih.gov/pubmed/37124148
http://dx.doi.org/10.1016/j.iotech.2023.100375