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The histamine H3 receptor modulates dopamine D2 receptor–dependent signaling pathways and mouse behaviors

The histamine H3 receptor (H3R) is highly enriched in the spiny projection neurons (SPNs) of the striatum, in both the D1 receptor (D1R)–expressing and D2 receptor (D2R)–expressing populations. A crossantagonistic interaction between H3R and D1R has been demonstrated in mice, both at the behavioral...

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Detalles Bibliográficos
Autores principales: Xu, Jian, Pittenger, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139999/
https://www.ncbi.nlm.nih.gov/pubmed/36871761
http://dx.doi.org/10.1016/j.jbc.2023.104583