DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC

To date, most studies on the DNA polymerase, POLD1, have focused on the effect of POLD1 inactivation mutations in tumors. However, the implications of high POLD1 expression in tumorigenesis remains elusive. Here, we determine that POLD1 has a pro-carcinogenic role in bladder cancer (BLCA) and is ass...

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Detalles Bibliográficos
Autores principales: Wang, Yejinpeng, Ju, Lingao, Wang, Gang, Qian, Kaiyu, Jin, Wan, Li, Mingxing, Yu, Jingtian, Shi, Yiliang, Wang, Yongzhi, Zhang, Yi, Xiao, Yu, Wang, Xinghuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140023/
https://www.ncbi.nlm.nih.gov/pubmed/37105989
http://dx.doi.org/10.1038/s41467-023-38160-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140023/
https://www.ncbi.nlm.nih.gov/pubmed/37105989
http://dx.doi.org/10.1038/s41467-023-38160-x

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