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BICD2 phosphorylation regulates dynein function and centrosome separation in G2 and M

The activity of dynein is regulated by a number of adaptors that mediate its interaction with dynactin, effectively activating the motor complex while also connecting it to different cargos. The regulation of adaptors is consequently central to dynein physiology but remains largely unexplored. We no...

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Detalles Bibliográficos
Autores principales: Gallisà-Suñé, Núria, Sànchez-Fernàndez-de-Landa, Paula, Zimmermann, Fabian, Serna, Marina, Regué, Laura, Paz, Joel, Llorca, Oscar, Lüders, Jens, Roig, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140047/
https://www.ncbi.nlm.nih.gov/pubmed/37105961
http://dx.doi.org/10.1038/s41467-023-38116-1