The genome-wide mutational consequences of DNA hypomethylation

DNA methylation is important for establishing and maintaining cell identity and for genomic stability. This is achieved by regulating the accessibility of regulatory and transcriptional elements and the compaction of subtelomeric, centromeric, and other inactive genomic regions. Carcinogenesis is ac...

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Detalles Bibliográficos
Autores principales: Besselink, Nicolle, Keijer, Janneke, Vermeulen, Carlo, Boymans, Sander, de Ridder, Jeroen, van Hoeck, Arne, Cuppen, Edwin, Kuijk, Ewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140063/
https://www.ncbi.nlm.nih.gov/pubmed/37106015
http://dx.doi.org/10.1038/s41598-023-33932-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140063/
https://www.ncbi.nlm.nih.gov/pubmed/37106015
http://dx.doi.org/10.1038/s41598-023-33932-3

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