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In vitro effects of gamma-secretase inhibition in HPV-positive and HPV-negative head and neck squamous cell carcinoma

BACKGROUND: New chemotherapy agents are warranted for head and neck squamous cell carcinoma (HNSCC), particularly for incidence-rising HPV-positive tumors. Based on the evidence of Notch pathway involvement in cancer promotion and progression, we aimed to gain insights into the in vitro antineoplast...

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Detalles Bibliográficos
Autores principales: Varatanovic, Sara, Maier, Tobias, Al-Gboore, Sega, Stoiber, Stefan, Kandathil, Sam Augustine, Quint, Clemens, Brennus, Charlotte, Heiduschka, Gregor, Kadletz-Wanke, Lorenz, Brkic, Faris F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140088/
https://www.ncbi.nlm.nih.gov/pubmed/36809443
http://dx.doi.org/10.1007/s10637-023-01334-x