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A novel pharmacological mechanism of anti-cancer drugs that induce pyroptosis

Pyroptosis is an inflammasome-induced lytic form of programmed cell death, and its main effect involves the release of inflammatory mediators when a cell dies, resulting in an inflammatory response in the body. The key to pyroptosis is the cleavage of GSDMD or other gasdermin families. Some drugs ca...

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Detalles Bibliográficos
Autores principales: Guo, Haohao, Wang, Ziyang, Ma, Runsheng, Chen, Xin, Li, Hongqiang, Tang, Yifeng, Du, Gongbo, Zhang, Yifei, Yin, Detao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140129/
https://www.ncbi.nlm.nih.gov/pubmed/36867378
http://dx.doi.org/10.1007/s10787-023-01148-6