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Bioactive fraction from Plumeria obtusa L. attenuates LPS-induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF-MS and molecular docking

In this study, the anti-inflammatory effects of the methanolic extract (TE) of Plumeria obtusa L. (aerial parts) and its fractions were evaluated in vitro, and active fraction was evaluated in vivo. Among tested extracts, dichloromethane fraction (DCM-F) exhibited the strongest inhibition of lipopol...

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Detalles Bibliográficos
Autores principales: Eloutify, Yousra T., El-Shiekh, Riham A., Ibrahim, Khaled Meselhy, Hamed, Ahmed R., Al-Karmalawy, Ahmed A., Shokry, Aya A., Ahmed, Yasmine H., Avula, Bharathi, Katragunta, Kumar, Khan, Ikhlas A., Meselhy, Meselhy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140140/
https://www.ncbi.nlm.nih.gov/pubmed/36773191
http://dx.doi.org/10.1007/s10787-023-01144-w