Integrated analysis of methylation profiles and transcriptome of Marek's disease virus-infected chicken spleens reveal hypomethylation of CD4 and HMGB1 genes might promote Marek's disease tumorigenesis

Marek's disease (MD) is a lymphoproliferative neoplastic disease caused by Marek's disease virus (MDV). Previous studies have showed that DNA methylation was involved in MD development, but systematic studies are still lacking. Herein, we performed whole genome bisulfite sequencing (WGBS)...

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Detalles Bibliográficos
Autores principales: Yuan, Yiming, Zheng, Gang, You, Zhen, Wang, Lulu, Wang, Ziyi, Sun, Congjiao, Liu, Changjun, Li, Xianyao, Zhao, Peng, Wang, Yongqiang, Yang, Ning, Lian, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
IMMUNOLOGY, HEALTH AND DISEASE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140160/
https://www.ncbi.nlm.nih.gov/pubmed/37043960
http://dx.doi.org/10.1016/j.psj.2023.102594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140160/
https://www.ncbi.nlm.nih.gov/pubmed/37043960
http://dx.doi.org/10.1016/j.psj.2023.102594

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