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Structures of calmodulin–melittin complexes show multiple binding modes lacking classical anchoring interactions
Calmodulin (CaM) is a Ca(2+) sensor protein found in all eukaryotic cells that regulates a large number of target proteins in a Ca(2+) concentration-dependent manner. As a transient-type hub protein, it recognizes linear motifs of its targets, though for the Ca(2+)-dependent binding, no consensus se...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140167/ https://www.ncbi.nlm.nih.gov/pubmed/36906144 http://dx.doi.org/10.1016/j.jbc.2023.104596 |