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Tissue clearing and three-dimensional imaging of the whole cochlea and vestibular system from multiple large-animal models

The inner ear of humans and large animals is embedded in a thick and dense bone that makes dissection challenging. Here, we present a protocol that enables three-dimensional (3D) characterization of intact inner ears from large-animal models. We describe steps for decalcifying bone, using solvents t...

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Detalles Bibliográficos
Autores principales: Moatti, Adele, Cai, Yuheng, Li, Chen, Popowski, Kristen D., Cheng, Ke, Ligler, Frances S., Greenbaum, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140170/
https://www.ncbi.nlm.nih.gov/pubmed/37060559
http://dx.doi.org/10.1016/j.xpro.2023.102220