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Tissue clearing and three-dimensional imaging of the whole cochlea and vestibular system from multiple large-animal models
The inner ear of humans and large animals is embedded in a thick and dense bone that makes dissection challenging. Here, we present a protocol that enables three-dimensional (3D) characterization of intact inner ears from large-animal models. We describe steps for decalcifying bone, using solvents t...
Autores principales: | Moatti, Adele, Cai, Yuheng, Li, Chen, Popowski, Kristen D., Cheng, Ke, Ligler, Frances S., Greenbaum, Alon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140170/ https://www.ncbi.nlm.nih.gov/pubmed/37060559 http://dx.doi.org/10.1016/j.xpro.2023.102220 |
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