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Aβ1-42-containing platelet-derived extracellular vesicle is associated with cognitive decline in Parkinson’s disease

BACKGROUND: Cortical amyloid deposition is a common observation in Parkinson’s disease dementia (PDD) patients. Aβ1-42 is linked to a more rapid progression of dementia. Platelets, which degranulate upon activation, are a primary source of Aβ. It has been repeatedly reported that peripheral extracel...

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Detalles Bibliográficos
Autores principales: Wang, Ziyu, Zheng, Yuanchu, Cai, Huihui, Yang, Chen, Li, Siming, Lv, Hong, Feng, Tao, Yu, Zhenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140302/
https://www.ncbi.nlm.nih.gov/pubmed/37122378
http://dx.doi.org/10.3389/fnagi.2023.1170663