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Accelerated hypometabolism with disease progression associated with faster cognitive decline among amyloid positive patients

OBJECTIVE: To evaluate the progression of brain glucose metabolism among participants with biological signature of Alzheimer’s disease (AD) and its relevance to cognitive decline. METHOD: We studied 602 amyloid positive individuals who underwent 18F-fluorodeoxyglucose PET (FDG-PET) scan, 18F-AV-45 a...

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Detalles Bibliográficos
Autores principales: Yang, Zhengshi, Cummings, Jeffrey L., Kinney, Jefferson W., Cordes, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140339/
https://www.ncbi.nlm.nih.gov/pubmed/37123373
http://dx.doi.org/10.3389/fnins.2023.1151820