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Bicarbonate boosts flash response amplitude to augment absolute sensitivity and extend dynamic range in murine retinal rods
Rod photoreceptors in the retina adjust their responsiveness and sensitivity so that they can continue to provide meaningful information over a wide range of light intensities. By stimulating membrane guanylate cyclases in the outer segment to synthesize cGMP at a faster rate in a Ca(2+)-dependent f...
Autores principales: | Adhikari, Rajan D., Kossoff, Amanda M., Cornwall, M. Carter, Makino, Clint L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140344/ https://www.ncbi.nlm.nih.gov/pubmed/37122625 http://dx.doi.org/10.3389/fnmol.2023.1125006 |
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