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CD4(+) T cell memory is impaired by species-specific cytotoxic differentiation, but not by TCF-1 loss
CD4(+) T cells are typically considered as ‘helper’ or ‘regulatory’ populations that support and orchestrate the responses of other lymphocytes. However, they can also develop potent granzyme (Gzm)-mediated cytotoxic activity and CD4(+) cytotoxic T cells (CTLs) have been amply documented both in hum...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140371/ https://www.ncbi.nlm.nih.gov/pubmed/37122720 http://dx.doi.org/10.3389/fimmu.2023.1168125 |