A (211)At-labelled mGluR1 inhibitor induces cancer senescence to elicit long-lasting anti-tumor efficacy

Metabotropic glutamate receptor 1 (mGluR1), a key mediator of glutamatergic signaling, is frequently overexpressed in tumor cells and is an attractive drug target for most cancers. Here, we present a targeted radiopharmaceutical therapy strategy that antagonistically recognizes mGluR1 and eradicates...

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Detalles Bibliográficos
Autores principales: Xie, Lin, Zhang, Lulu, Hu, Kuan, Hanyu, Masayuki, Zhang, Yiding, Fujinaga, Masayuki, Minegishi, Katsuyuki, Ohkubo, Takayuki, Nagatsu, Kotaro, Jiang, Cuiping, Shimokawa, Takashi, Ashisuke, Kazuma, Okonogi, Noriyuki, Yamada, Shigeru, Wang, Feng, Wang, Rui, Zhang, Ming-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140459/
https://www.ncbi.nlm.nih.gov/pubmed/37003259
http://dx.doi.org/10.1016/j.xcrm.2023.100960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140459/
https://www.ncbi.nlm.nih.gov/pubmed/37003259
http://dx.doi.org/10.1016/j.xcrm.2023.100960

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