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Myc controls NK cell development, IL-15-driven expansion, and translational machinery

MYC is a pleiotropic transcription factor involved in cancer, cell proliferation, and metabolism. Its regulation and function in NK cells, which are innate cytotoxic lymphocytes important to control viral infections and cancer, remain poorly defined. Here, we show that mice deficient for Myc in NK c...

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Detalles Bibliográficos
Autores principales: Khameneh, Hanif J, Fonta, Nicolas, Zenobi, Alessandro, Niogret, Charlène, Ventura, Pedro, Guerra, Concetta, Kwee, Ivo, Rinaldi, Andrea, Pecoraro, Matteo, Geiger, Roger, Cavalli, Andrea, Bertoni, Francesco, Vivier, Eric, Trumpp, Andreas, Guarda, Greta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140547/
https://www.ncbi.nlm.nih.gov/pubmed/37105715
http://dx.doi.org/10.26508/lsa.202302069