Cargando…
Myc controls NK cell development, IL-15-driven expansion, and translational machinery
MYC is a pleiotropic transcription factor involved in cancer, cell proliferation, and metabolism. Its regulation and function in NK cells, which are innate cytotoxic lymphocytes important to control viral infections and cancer, remain poorly defined. Here, we show that mice deficient for Myc in NK c...
Autores principales: | Khameneh, Hanif J, Fonta, Nicolas, Zenobi, Alessandro, Niogret, Charlène, Ventura, Pedro, Guerra, Concetta, Kwee, Ivo, Rinaldi, Andrea, Pecoraro, Matteo, Geiger, Roger, Cavalli, Andrea, Bertoni, Francesco, Vivier, Eric, Trumpp, Andreas, Guarda, Greta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140547/ https://www.ncbi.nlm.nih.gov/pubmed/37105715 http://dx.doi.org/10.26508/lsa.202302069 |
Ejemplares similares
-
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells
por: Niogret, Charlène, et al.
Publicado: (2019) -
SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling
por: Niogret, Charlène, et al.
Publicado: (2019) -
NLRC5 promotes transcription of BTN3A1-3 genes and Vγ9Vδ2 T cell-mediated killing
por: Dang, Anh Thu, et al.
Publicado: (2020) -
Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses
por: Ventura, Pedro M O, et al.
Publicado: (2022) -
NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions
por: Ludigs, Kristina, et al.
Publicado: (2016)