Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis

Loss of function of inhibitory immune checkpoints, unleashing pathogenic immune responses, is a potential risk factor for autoimmune disease. Here, we report that patients with the autoimmune vasculitis giant cell arteritis (GCA) have a defective CD155-CD96 immune checkpoint. Macrophages from patien...

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Detalhes bibliográficos
Autores principales: Ohtsuki, Shozo, Wang, Chenyao, Watanabe, Ryu, Zhang, Hui, Akiyama, Mitsuhiro, Bois, Melanie C., Maleszewski, Joseph J., Warrington, Kenneth J., Berry, Gerald J., Goronzy, Jörg J., Weyand, Cornelia M.
Formato: Online Artigo Texto
Idioma:English
Publicado em: Elsevier 2023
Assuntos:
Article
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140609/
https://www.ncbi.nlm.nih.gov/pubmed/37075705
http://dx.doi.org/10.1016/j.xcrm.2023.101012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140609/
https://www.ncbi.nlm.nih.gov/pubmed/37075705
http://dx.doi.org/10.1016/j.xcrm.2023.101012

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