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Can regulatory T cells improve outcomes of sensitised patients after HLA-Ab incompatible renal transplantation: study protocol for the Phase IIa GAMECHANgER-1 trial

BACKGROUND: Kidney transplantation is the gold-standard treatment for patients with kidney failure. However, one-third of patients awaiting a kidney transplant are highly sensitized to human leukocyte antigens (HLA), resulting in an increased waiting time for a suitable kidney, more acute and chroni...

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Detalles Bibliográficos
Autores principales: Dudreuilh, C, Jarvis, P, Beadle, N, Pilecka, I, Shaw, O, Gardner, L, Scottà, C, Mamode , N, Game, DS, Sanchez-Fueyo, A, Lombardi, G, Learoyd, A, Douiri, A, Dorling, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140710/
https://www.ncbi.nlm.nih.gov/pubmed/37118685
http://dx.doi.org/10.1186/s12882-023-03157-7