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Shp2 Deficiency in Kupffer Cells and Hepatocytes Aggravates Hepatocarcinogenesis by Recruiting Non-Kupffer Macrophages

BACKGROUND & AIMS: Complex communications between hepatocytes and Kupffer cells (KCs) are known to drive or suppress hepatocarcinogenesis, with controversial data in the literature. In previous experiments that aimed to decipher hepatocyte/KC interactions, we unexpectedly unveiled a tumor-suppre...

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Detalles Bibliográficos
Autores principales: Du, Li, Ji, Yichun, Xin, Bing, Zhang, Jiemeng, Lu, Li-Chun, Glass, Christopher K., Feng, Gen-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140795/
https://www.ncbi.nlm.nih.gov/pubmed/36828281
http://dx.doi.org/10.1016/j.jcmgh.2023.02.011