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Binding Parameters of [(11)C]MPC-6827, a Microtubule-Imaging PET Radiopharmaceutical in Rodents

Impairment and/or destabilization of neuronal microtubules (MTs) resulting from hyper-phosphorylation of the tau proteins is implicated in many pathologies, including Alzheimer’s disease (AD), Parkinson’s disease and other neurological disorders. Increasing scientific evidence indicates that MT-stab...

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Detalles Bibliográficos
Autores principales: Bansode, Avinash H., Bhoopal, Bhuvanachandra, Gollapelli, Krishna Kumar, Damuka, Naresh, Krizan, Ivan, Miller, Mack, Craft, Suzanne, Mintz, Akiva, Solingapuram Sai, Kiran Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140836/
https://www.ncbi.nlm.nih.gov/pubmed/37111252
http://dx.doi.org/10.3390/ph16040495